Haplotype-Specific DNA Methylation
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Autoimmune hepatitis type-1

hits  2

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1  rs2187668  chr6:32605883-32605884
genes 4 GWAS disease/phenotype 5
rs2187668

LD Block:  chr6:32384800-32681631

Genes:

  • HLA-DQA1
  • HLA-DQB1
  • HLA-DR3
  • HLA-DRB1

GWAS Disease/Phenotype:

  • Autoimmune hepatitis type-1
  • Celiac disease
  • Immunoglobulin A
  • Nephropathy (idiopathic membranous)
  • Systemic lupus erythematosus

2  rs3184504  chr12:111884607-111884608
genes 7 GWAS disease/phenotype 10
rs3184504

LD Block:  chr12:111358233-112615538

Genes:

  • ATXN2
  • BRAP
  • C12orf51
  • LOC100101246
  • NAA25
  • PTPN11
  • SH2B3

GWAS Disease/Phenotype:

  • Autoimmune hepatitis type-1
  • Beta-2 microglubulin plasma levels
  • Diastolic blood pressure
  • Eosinophil counts
  • Hypothyroidism
  • Platelet counts
  • Red blood cell traits
  • Systolic blood pressure
  • Type 1 diabetes
  • Type 1 diabetes autoantibodies

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